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By Target- Apoptosis
- HIV Protease(1)
- P2X Receptor(1)
- Sodium Channel(1)
- TRP/TRPV Channel(1)
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Results for "
hma5
" in TargetMol Product Catalog- Inhibitors & Agonists1
5-(N,N-Hexamethylene)-amiloride
HMA-5, Hexamethylene amiloride, 5-HMA, 5-(N,N-Hexamethylene)amiloride
T46991428-95-1In house
5-(N,N-Hexamethylene)-amiloride (5-HMA) is an amiloride derivative that inhibits TRPA1-mediated calcium signaling (IC50: 35 μM). It functions as an inhibitor of the Na+ H+ exchanger (NHE) with Ki values ranging from 0.013 to 2.4 μM for various NHE isoforms. Additionally, 5-HMA blocks ASIC3 channels by 51% at 20 μM.
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