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By Target- Apoptosis
- IAP(1)
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Results for "
hm 90822
" in TargetMol Product Catalog- Inhibitors & Agonists2
HM90822
HM-90822, HM 90822
T708681363145-46-3In house
HM90822 is a novel synthetic apoptotic protein (IAP) antagonist that induces apoptosis in human pancreatic cancer cells through proteasome-dependent degradation of IAPs containing the BIR2 3 structural domain.HM90822 inhibits the expression of XIAP and cIAP1 2 proteins in HM822-sensitive Panc-1 and BxPC-3 cells, induces ubiquitylation of IAPs and promotes induces IAP ubiquitination and promotes proteasome-dependent IAP degradation.
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