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Results for "
hj-591
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Inhibitory Antibodies1
Rosopatamab
HJ591, HJ 591
T782862260767-49-3
Rosopatamab is a humanized monoclonal antibody targeting prostate-specific membrane antigen (PSMA) for the treatment of prostate cancer. It can be conjugated with radiolabeled isotopes (e.g., 177Lu) via DOTA-NHS ester to form radiopharmaceuticals for targeted therapy. In preclinical studies, 177Lu-DOTA-Rosopatamab combined with the DNA-PK inhibitor Peposertib achieved a 75% complete response rate in prostate cancer mouse models.
- $247
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