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  • GPCR
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hca2 (hydroxy-carboxylic acid receptor 2)

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
GSK256073
T15432862892-90-8
GSK256073 is an orally active GPR109A agonist. GSK256073 also is a long-lasting and non-flushing HCA2 (hydroxy-carboxylic acid receptor 2) full agonist (pEC50: 7.5). GSK256073 acutely improves glucose homeostasis via inhibition of lipolysis.
  • $67
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MK 1903
T229861268882-43-4
MK 1903 is a potent and selective complete agonist for the hydroxy-carboxylic acid receptor 2 (HCA2). HCA2 is also known as G protein-coupled receptor 109A(GPR109A). MK 1903 reduced Foschlin-induced cAMP production in uniform time-resolved fluorescence (htf) measurements using CHO cells expressing the human receptor (ECso-12.9 nM).
  • $35
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