hbpep(rpy)spacetate

HBpep(RPY)-SP acetate is a modified HBpep-SP peptide that forms co-condensate microdroplets by liquid-liquid phase separation and directly crosses the cell membrane, independently of the classical endocytosis pathway, thus enabling intracellular delivery and efficient release of biomolecules (e.g., peptides, proteins, and mRNAs), and it can also be used for transfection.

HBpep(RPY)-SP is a variant of the polypeptide HBpep-SP. This compound interacts with lipid bilayers and has demonstrated exceptional transfection efficiency in challenging-to-transfect cells, such as primary and immune cells. HBpep(RPY)-SP is useful for research in protein, gene, and immune cell therapies.

HBpep(RPY)-SP TFA is an optimized phase-separating peptide capable of liquid-liquid phase separation to form conjugated microdroplets over a wide pH range (6.5-9.0). It is highly efficient in the delivery of a wide range of biomolecules and can be used in difficult-to-transfect cells.