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haematological malignancies

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
Tirabrutinib hydrochloride
ONO-4059 (hydrochloride), GS-4059 (hydrochloride)
T123111439901-97-9
Tirabrutinib hydrochloride is a potent, highly selective, and irreversible oral BTK inhibitor. Tirabrutinib hydrochloride irreversibly covalently binds to Bruton tyrosine kinase (BTK) in B cells and exhibits potent in vitro cytotoxicity against many types of B cell malignancies, as well as in vivo antitumor activity in mouse models [1].
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Umbralisib
TGR-1202, TGR1202, TGR 1202, RP5264
T49761532533-67-7
Umbralisib (TGR 1202) is a PI3Kδ inhibitor.
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