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Results for "
h-ser-his-oh
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Peptide Products2
H-Ser-His-OH
T1152767726-09-4
H-Ser-His-OH, an endogenous metabolite, is a short peptide with hydrolysis cleavage activity.
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H-Ser-His-OH acetate
T11527L
H-Ser-His-OH acetate is an endogenous metabolite hydrolysis cleavage activity.
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[Leu144, Arg147]-PLP (139-151) TFA
[Leu144, Arg147] Proteolipid Peptide (139-151), H-His-Ser-Leu-Gly-Lys-Leu-Leu-Gly-Arg-Pro-Asp-Lys-Phe-OH
T83690
[Leu144,Arg147]-PLP (139-151) is a mutated fragment of the myelin proteolipid protein (PLP), featuring substitutions of tryptophan to leucine and histidine to arginine at positions 144 and 147, respectively. Immunizing mice with this peptide (50 µg) mixed in complete Freund's adjuvant (CFA) elevates IL-4 levels in the spleen. While it suppresses Th1 cell activation in vitro, it does not do so in vivo; instead, it promotes the development of regulatory T cells. Preimmunization with [Leu144, Arg147]-PLP (139-151) postpones the onset of experimental autoimmune encephalomyelitis (EAE) triggered by encephalitogenic peptides from PLP (178-191), myelin oligodendrocyte glycoprotein (MOG) (92-106), or myelin basic protein (MBP) in mice.
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