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By Target- PDGFR
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Results for "
gzd-856
" in TargetMol Product Catalog- Inhibitors & Agonists1
T640872804039-78-7
GZD856 formic is a potent, orally active inhibitor of PDGFRα/β and Bcr-Abl T315I, demonstrating IC50 values of 68.6 nM and 136.6 nM for PDGFRα/β, respectively, and 19.9 nM and 15.4 nM for native Bcr-Abl and the T315I mutant, respectively. This compound exhibits significant antitumor activity.
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