gut microbiome

2'-FUCOSYLLACTOSE (2'-Fucosyl-D-lactose) is a fucose-containing oligosaccharide.

Masticadienonic acid is a compound derived from Chios mastic gum, with potential anti-inflammatory and anti-cancer activities. It alleviates colitis in mice by modulating inflammatory responses, gut barrier integrity, and the microbiome. Masticadienonic acid is a potential protein tyrosine phosphatase 1B (PTP1B) inhibitor and can be used for research on diabetes.

Pyrocatechol sulfate, a phenolic metabolite found in human plasma, is associated with the intake of specific foods such as berries and the state of the gut microbiome. It serves as a potential urinary biomarker for kidney function, dialysis clearance rates, whole grain consumption, and regular coffee intake. Additionally, in conjunction with other phenolic sulfates, pyrocatechol sulfate plays a role in regulating various biological functions, including those related to brain health and the rhythmic beating of cardiac cells.

Antibacterialagent 231 (derivative 8) is an antimicrobial compound effective against multidrug-resistant Helicobacter pylori (H. pylori), with a minimum inhibitory concentration ranging from 0.25 to 0.5 μg/mL. It specifically targets the protein translocase subunit SecA and the outer membrane protein assembly factor BamD to inhibit the transport and assembly of bacterial outer membrane proteins (OMPs). Antibacterialagent 231 is suitable for studying the effects of antibiotic treatment on gut microbiome balance.

Compound 6d (Antibacterial agent 159) is an antibiotic effective against impetigo and Clostridium difficile infection (CDI), with no observed recurrence for CDI and minimal impact on the beneficial gut microbiome [1].