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gsk321

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
GSK321
GSK-321, GSK 321
T320091816331-63-1
GSK321 is a selective and potent mutant isocitrate dehydrogenase 1 (IDH1) inhibitor that inhibits lipid synthesis and blocks cell proliferation in OPA1-deficient MEFs and prevents cytoplasmic glutamine reductive carboxylation.GSK321 has been used in the study of leukemia.
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8-10 weeks
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(S,S)-GSK321
T739291816272-20-4
(S,S)-GSK321 is the (S,S)-enantiomer of GSK321 [1].
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WT IDH1 Inhibitor 2
T634031816272-19-1
WT IDH1 Inhibitor 2 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor (IC50: 120 nM) and is a mutant R132H IDH1 inhibitor, an isoform of GSK321 with wild-type cross-reactivity.
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8-10 weeks
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