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gsk2118436

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
Dabrafenib
GSK2118436A, GSK2118436
T19031195765-45-7
Dabrafenib (GSK2118436A) is a Raf inhibitor that inhibits C-Raf and B-RafV600E (IC50=5 0.6 nM) and is ATP-competitive. Dabrafenib exhibits antitumor activity for the treatment of B-RafV600E-mutated melanoma.
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Dabrafenib Mesylate
GSK2118436 Mesylate, GSK 2118436B
T84741195768-06-9
Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively).
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