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gsk1379767a

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
GSK1379767A
T701711802251-02-0
GSK1379767A is a dual inhibitor of BPTF and Brd4.
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6-8 weeks
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Milvexian TFA
T701701802426-00-1
Milvexian, also known as BMS-986177 and JNJ-70033093, is a blood coagulation factor XIa inhibitor. Milvexian demonstrated good selectivity over plasma kallikreinKi = 44 nM (400-fold selective), and chymotrypsinKi = 35 nM (318-fold selective). At a dose of 1.5 mg kg, Milvexian exhibited an overall exposure of 1215 nM h, low clearance of 10.3 mL min kg, and oral bioavailability of 32%.
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6-8 weeks
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