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gpr120 agonist 2

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
GPR120 Agonist 2
GPR120 receptor agonist
T43121234844-11-1
GPR120 Agonist 2 is a potent and selective GPR120 receptor agonist.
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ZQ 16
T36634376616-73-8
Selective medium-chain free fatty acid receptor GPR84 agonist (EC50 = 139 nM). Exhibits no response at GPR40, GPR41, GPR119 or GPR120 at 100 μM. Activates calcium mobilization, inhibits cAMP accumulation, and induces ERK1/2 phosphorylation, receptor desensitization and internalization in vitro. Liu et al (2016) Design and synthesis of 2-alkylpyrimidine-4,6-diol and 6-alkylpyridine-2,4-diol as potent GPR84 agonists. ACS Med.Chem.Lett. 7 579 PMID:27326330 |Zhang et al (2016) Discovery and characterization of a novel small-molecule agonist for medium-chain free fatty acid receptor G protein-coupled receptor 84. J.Pharmacol.Exp.Ther. 357 337 PMID:26962172
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7-10 days
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