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gpa-1734 bromide

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  • Inhibitors & Agonists
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GPA-1734 bromide
T6982721852-25-5
GPA-1734 bromide is an inhibitor of basement membrane collagen synthesis and angiogenesis.
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6-8 weeks
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(2Z,3Z)-U0126
T69826218601-62-8
(2Z,3Z)-U0126 is a highly selective inhibitor of both MEK1 and MEK2, a type of MAPK ERK kinase. It was found to functionally antagonize AP-1 transcriptional activity via noncompetitive inhibition of the dual specificity kinase MEK with IC50 of 72 nM for MEK1 and 58 nM for MEK2. U0126 inhibited anchorage-independent growth of Ki-ras-transformed rat fibroblasts by simultaneously blocking both extracellular signal-regulated kinase and mammalian target of rapamycin pathways.
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6-8 weeks
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