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Results for "
gne 431
" in TargetMol Product Catalog- Inhibitors & Agonists2
Alnespirone hydrochloride
T70666143413-68-7
Alnespirone hydrochloride is a selective 5-HT1A receptor full agonist of the azapirone chemical class. It has both antidepressant and anxiolytic effects.
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GNE-431
T706681433820-83-7
GNE-431 is a potent, selective and noncovalent Btk inhibitor with IC50 of 3.2 nM. GNE-431 showed excellent potency against the C481R, T474I, and T474M mutants. GNE-431 may provide a treatment option to patients, especially those who have acquired resistance to ibrutinib by mutation of Cys481 or Thr474.
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