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glyrs

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GlyRS-IN-1
T11434112921-11-6
GlyRS-IN-1 is a glycyl-tRNA synthase (GlyRS) inhibitor disclosed in patent WO 2017066459 A1, and functions by disrupting aminoacyl-tRNA biosynthesis, thereby impairing protein synthesis; GlyRS-IN-1 also suppresses bacterial growth, making it a valuable chemical probe for studying translational machinery, antimicrobial target validation, and the development of novel antibiotics against resistant bacterial pathogens.
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Colchicine-d3
TMID-10771217625-62-1
Colchicine-d3 is the deuterated form of Colchicine. Colchicine acts as a microtubule protein (tubulin) inhibitor and disruptor of microtubules (microtubule), with an IC50 of 3 nM for inhibiting microtubule polymerization. Additionally, Colchicine serves as a competitive antagonist of the α3 glycine receptor (GlyRs).
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