geranylgeranyl pyrophosphate (ammonium salt)

Farnesyl pyrophosphate-d2 (Farnesyl diphosphate-d2) triammonium is the deuterium-labeled version of Farnesyl pyrophosphate triammonium. This compound, also known as Farnesyl pyrophosphate ammonium salt, is a 15-carbon isoprenoid and a metabolic intermediate in the mevalonate (MVA) pathway. It acts as an agonist of TRPM2 (TRP Channel), enabling the channel to open and allowing ion flow into cells. Additionally, Farnesyl pyrophosphate ammonium salt serves as a crucial branching substrate for cholesterol synthesis, ubiquinone synthesis, protein prenylation, and the synthesis of geranylgeranyl pyrophosphate (GGPP).

Geranylgeranyl Pyrophosphate triammonium (GGPP triammonium) is a metabolite involved in protein geranylgeranylation, modulating endothelial cell proliferation and apoptosis during mouse embryonic angiogenesis. GGPP triammonium amplifies T(reg) differentiation by increasing IL-2 expression, improving DSS-induced colitis, useful in cancer research.

Farnesyl pyrophosphate-d2 (Farnesyl diphosphate-d2) triammonium is a deuterium-labeled variant of farnesyl pyrophosphate triammonium. This 15-carbon isoprenoid serves as a metabolic intermediate in the mevalonate (MVA) pathway. Additionally, farnesyl pyrophosphate ammonium salt acts as an agonist for the TRPM2 (TRP Channel), facilitating ion entry into cells. It is also a crucial substrate for cholesterol synthesis, ubiquinone synthesis, protein farnesylation, and geranylgeranyl pyrophosphate (GGPP) production.