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gedatolisib

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
gedatolisib
PKI-587, PF-05212384
T19701197160-78-3
Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα γ (IC50: 0.4 5.4 nM)and mTOR (IC50: 1.6 nM) in the PI3K mTOR signaling pathway.
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PI3K/mTOR Inhibitor-7
T640412456295-65-9
PI3K mTOR Inhibitor-7 is a potent dual PI3K mTOR inhibitor. PI3K mTOR Inhibitor-7 is 4.7-fold more potent than gedatolisib, with IC50 values of 1.4 μM and 0.3 μM, respectively. 10 μM of PI3K mTOR Inhibitor-7 is able to significantly inhibit the PI3K Akt mTOR signalling pathway. PI3K mTOR Inhibitor-7 has shown potential for research in cancer diseases.
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8-10 weeks
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PI3K/mTOR Inhibitor-6
T642192456295-59-1
PI3K mTOR Inhibitor-6 (Compound 19c) is a potent dual PI3K mTOR inhibitor, exhibiting greater stability than gedatolisib in artificial gastric fluid. At 10 μM, PI3K mTOR Inhibitor-6 significantly inhibits the PI3K Akt mTOR signaling pathway and has shown potential for cancer research.
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8-10 weeks
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