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gb-88

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
GB-88
GB88, GB 88
T113701416435-96-5
GB-88 is an orally active, highly selective, non-peptide PAR2 antagonist that blocks downstream inflammatory and pain signaling pathways by inhibiting PAR2-mediated Ca²⁺ release (IC₅₀ = 2 μM). GB-88 exhibits antagonistic activity against various PAR2 agonists, including trypsin, SLIGRL-NH₂, and GB110, and shows no significant cross-reactivity with PAR1, PAR3, or PAR4. GB-88 is suitable for research into diseases such as inflammation, pain, and metabolic disorders.
  • $446
7-10 days
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