gastrointestinal dysfunction

CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.

Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. Also, Momordin Ic accelerates gastrointestinal transit partially by stimulating synthesis of 5-HT to act through 5-HT(2), which, in turn, increases synthesis of prostaglandins.

DSP-6952 is a 5-HT4 receptor partial agonist, inhibiting visceral hypersensitivity and ameliorating gastrointestinal dysfunction.

Catechin 7-O-β-D-glucopyranoside is a major bioactive constituent associated with antioxidant and anti-inflammatory benefits of PHCR seed extracts and has been recognized as a promising research agent for intestinal inflammatory disorders. Catechin 7-O-β-D-glucopyranoside demonstrates strong biological effects supporting future pharmaceutical development of CGP-containing formulations against gastrointestinal inflammatory diseases.

Momordin Ic (Standard) is a reference standard for research and analysis in studies involving Momordin Ic. Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways. Also, Momordin Ic accelerates gastrointestinal transit partially by stimulating synthesis of 5-HT to act through 5-HT(2), which, in turn, increases synthesis of prostaglandins.