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By Target- Amino Acids and Derivatives
- Antibacterial(1)
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Results for "
gastric mucin
" in TargetMol Product Catalog- Inhibitors & Agonists3
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- Recombinant Protein2
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- Cell Research2
Gastric mucin
TP130984082-64-4
Gastric mucin, a large glycoprotein, is thought to play a major role in protecting the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma. Gastric mucin is a natural protein derived from pigs.
- $40
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N-Acetylgalactosaminyltransferase 1
GALNT1
TRP-00404
N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring α-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer enhances the aberrant O-glycosylation of CD44, activating the Wnt/β-catenin signaling pathway and influencing the malignant behavior of gastric cancer cells. This enzyme plays a crucial role in cancer progression and metastasis by modifying the O-glycosylation of various glycoproteins such as mucin (MUC1), osteopontin (OPN), matrix metalloproteinase-14 (MMP14), and integrin α3.
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