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By Target- ATM/ATR
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Results for "
gartisertib
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- Isotope Products1
- GartisertibVX-803, VX 03, VRT1228692, M4344, M 4344, ATR inhibitor 2T104071613191-99-3In houseGartisertib (VX-803) is an orally active and selective Rad3-related protein (ATR) inhibitor with antitumor activity, inhibiting the antiproliferative effect induced in ccRCC cells, and inhibiting ATR-driven phosphorylation of checkpoint kinase 1 (Chk1), useful for studying solid tumors.
- $129
SizeQTY - Gartisertib-d8VX-803-d8, M4344-d8, ATR inhibitor 2-d8TMIT-04831792214-00-6Gartisertib-d8 (VX-803-d8) is the deuterated form of Gartisertib. Gartisertib (VX-803) acts as an orally active, selective ATP-competitive ATR inhibitor, with a Ki of less than 150 pM. It effectively inhibits ATR-driven phosphorylation of checkpoint kinase-1 (Chk1), with an IC50 value of 8 nM, and exhibits antitumor activity.
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