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galunisertib

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
Galunisertib
LY2157299
T2510700874-72-2
Galunisertib (LY2157299) is a TGF-β receptor type I (TGF-βRI) inhibitor (IC50=56 nM) that is selective. Galunisertib has antitumor activity and can be used in combination with PD-1 inhibitors.
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TargetMol | Inhibitor Hot
Galunisertib Monohydrate
T68333924898-09-9
Galunisertib Monohydrate is a first-in-class transforming growth factor-β receptor type I inhibitor.
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6-8 weeks
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HYL001
T2004612426547-83-1
HYL001 (compound 338) is a potent inhibitor of the TGFβ receptor 1 (ALK5), exhibiting approximately nine times the efficacy of its structurally related counterpart, galunisertib, in eliminating liver metastasis tumors generated in mice.
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4-6 weeks
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