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g1t38 dihydrochloride

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Lerociclib dihydrochloride
G1T38 dihydrochloride
T11345L2097938-59-3
Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective CDK4 CDK6 inhibitor, with IC50 values of 2 nM for CDK6 CyclinD3 and 1 nM for CDK4 CyclinD1.
  • $31
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Lerociclib
G1T-38, G1T38, G1T 38
T113451628256-23-4
Lerociclib (G1T38) is a selective and highly potent CDK4/6 inhibitor with anticancer and antitumor activity, inhibits CDK4/CyclinD1 and CDK6/CyclinD3, and inhibits tumor growth in an animal model of endocrine-resistant breast cancer. Due to the poor solubility, for animal studies, the salt form T11345L is recommended.
  • $34
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