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fitusiran

" in TargetMol Product Catalog.
  • Inhibitors & Agonists
    2
    TargetMol | All_Pathways
  • Fitusiran
    SAR-439774, SAR439774, SAR 439774, ALN-AT3SC
    T389861499251-18-1
    Fitusiran (ALN-AT3SC) is a small interfering RNA therapeutic designed to selectively bind antithrombin messenger RNA in the liver, leading to sustained reduction of antithrombin production and enhanced thrombin generation, thereby offering a mechanistically innovative research approach for restoring hemostatic balance in hemophilia models.
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  • GalNAc unconjugated/naked Fitusiran
    T74877
    GalNAc unconjugated/naked Fitusiran, an small interfering RNA without GalNAc conjugation, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. GalNAc unconjugated/naked Fitusiran increases thrombin generation and has the potential for the research of the hemophilia [1] .
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