eurycoma

Eurycomanone (Pasakbumin A) is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibits A549 lung cancer cell proliferation in a dose-dependent manner at concentrations ranging from 5 to 20 μg ml.

Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα β and IκBα.

13,21-Dihydroeurycomanone (Pasakbumin C) is a natural product isolated from the root of Eurycoma longifolia with antiparasitic activity such as Plasmodium falciparum and Toxoplasma gondii.

Eurycomanol 2-O-β-D-glucopyranoside, a natural diterpenoid compound, is extracted from Tongkat Ali.

Eurycomalide A is a useful organic compound for research related to life sciences and the catalog number is T124417.

Eurycomalin A is a useful organic compound for research related to life sciences and the catalog number is T124210.

Canthin-6-one N-oxide has broad spectrum antifungal, leishmanicidal and trypanocidal activities.

14,15 β-Dihydroxyklaineanone(14,15beta-Dihydroxyklaineanone) is a bittersweet compound isolated from Eurycoma longifolia with antitumor-promoting, antischistosomal and plasmodium-killing activities.

1-Methoxymethyl-β-carboline, a natural product, has been isolated from the root of Eurycoma longifolia [1].

Pasakbumin B (13-alpha-(21)-Epoxyeurycomanone) is a bioactive compound from Eurycoma longifolia Jack.

7-Methoxy-β-carboline-1-propionic acid (compound 46), recognized for its cytotoxic and antimalarial properties, is derived from the roots of Eurycoma longifolia [1].