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(3)
By Target- Apoptosis
- Histone Methyltransferase(3)
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By Target By ResearchField- Cancer(2)
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Results for "
epz-004777
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- Oligonucleotides2
EPZ004777
Cited
T30811338466-77-5
EPZ004777 is a potent and selective DOT1L inhibitor with an IC50 of 0.4 nM.
- $33
Size
QTY
CitedEPZ004777 hydrochloride
EPZ004777 HCl
T3081L1380316-03-9
EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
- $68
Size
QTY
EPZ004777 formate
T214051
EPZ004777 formate is an effective and selective DOT1L inhibitor with an IC50 of 0.4 nM. It reduces levels of H3K79me2 and H3K79me1, significantly downregulating the expression of HOXA9 and MEIS1. This compound selectively inhibits the proliferation of MLL-rearranged cells and induces differentiation followed by apoptosis in leukemia cells, making it useful for leukemia research.
- Inquiry Price
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