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By Target- Glucocorticoid Receptor
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Results for "
eplerenone
" in TargetMol Product Catalog- Inhibitors & Agonists3
Eplerenone
SC-66110, Epoxymexrenone, CGP 30083
T0083107724-20-9
Eplerenone (CGP 30083) is an aldosterone receptor antagonist and potassium-sparing diuretic used in the therapy of hypertension. Eplerenone therapy has been associated with transient elevations in serum aminotransferase levels, but has yet to be linked to cases of clinically apparent drug induced liver disease.
- $44
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QTY
21-hydroxy Eplerenone
T36129334678-67-0
21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone . It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4.
- $838
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6β-hydroxy Eplerenone
T37064209253-80-5
6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone .1 It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4. |1. Cook, C.S., Berry, L.M., Kim, D.H., et al. Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: Differential metabolism by CYP3A4 and CYP3A5. Drug Metab. Dispos. 30(12), 1344-1351 (2002).
- $1,120
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