enniatin a1

Enniatin A1, a cyclic hexadepsipeptide composed of alternating D-α-hydroxyisovaleric acids and N-methyl-L-amino acids isolated from Fusarium mycotoxins, exhibits anticarcinogenic effects through the induction of apoptosis and disruption of the ERK signaling pathway. It also inhibits ACAT in rat liver microsomes with an IC₅₀ of 49 μM.

Enniatin A1-13C35 is the 13C-labeled version of Enniatin A1. This cyclic hexadepsipeptide is derived from Fusarium fungus mycotoxins and consists of alternating D-α-hydroxyisovaleric acid and N-methyl-L-amino acids. Enniatin A1 exhibits anticancer properties by inducing apoptosis and disrupting the ERK signaling pathway. In rat liver microsomes, Enniatin A1 inhibits ACAT with an IC₅₀ of 49 μM.

Enniatin A-13C36 is a version of Enniatin A labeled with 13C. Enniatin A is a fusarium toxin that inhibits acyl-CoA:cholesterol acyltransferase (ACAT) activity in rat liver microsomal enzyme assays, with an IC₅₀ of 22 μM.