enniatin a

Enniatin A, a Fusarium mycotoxin, inhibits acyl-CoA: cholesterol acyltransferase (ACAT) with an IC50 of 22 μM in rat liver microsome enzyme assays.

Enniatin F is a natural product that can be used as a reference standard. The CAS number of Enniatin F is 144446-20-8.

Enniatin A1, a cyclic hexadepsipeptide composed of alternating D-α-hydroxyisovaleric acids and N-methyl-L-amino acids isolated from Fusarium mycotoxins, exhibits anticarcinogenic effects through the induction of apoptosis and disruption of the ERK signaling pathway. It also inhibits ACAT in rat liver microsomes with an IC50 of 49 μM.

Enniatin A-13C36 is a version of Enniatin A labeled with 13C. Enniatin A is a fusarium toxin that inhibits acyl-CoA:cholesterol acyltransferase (ACAT) activity in rat liver microsomal enzyme assays, with an IC50 of 22 μM.

Enniatin A1-13C35 is the 13C-labeled version of Enniatin A1. This cyclic hexadepsipeptide is derived from Fusarium fungus mycotoxins and consists of alternating D-α-hydroxyisovaleric acid and N-methyl-L-amino acids. Enniatin A1 exhibits anticancer properties by inducing apoptosis and disrupting the ERK signaling pathway. In rat liver microsomes, Enniatin A1 inhibits ACAT with an IC50 of 49 μM.

Enniatin C is a membrane-active antibiotic with antimalarial activity that inhibits Mycobacterium tuberculosis, used in the study of fungal infections.

Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it has demonstrated the ability to induce apoptosis in multiple cancer cell lines. In addition to these activities, the Enniatin complex possesses ionophoric, antibiotic, and in vitro hypolipidemic properties.

Enniatins B decreases the activation of ERK (p44/p42). Enniatin B is a Fusarium mycotoxin. Enniatin B inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 113 μM in an enzyme assay using rat liver microsomes.

Enniatin B1, a Fusarium mycotoxin, crosses the blood-brain barrier, decreases the activation of ERK (p44/p42), and inhibits moderately TNF-α-induced NF-κB activation. Furthermore, it inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity, exhibiting an IC50 of 73 μM in rat liver microsome enzyme assays.

Enniatin B1-13C34 is a 13C-labeled version of Enniatin B1. Enniatin B1, a mycotoxin produced by Fusarium species, inhibits acyl-CoA:cholesterol acyltransferase (ACAT) activity in rat liver microsomes with an IC50 of 73 μM. It can cross the blood-brain barrier and reduces ERK (p44/p42) activation, while also inhibiting TNF-α-induced NF-κB activation.

Enniatin B-13C33 is the carbon-13 labeled version of Enniatin B, a mycotoxin produced by Fusarium species. It acts as an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) activity in rat liver microsomal enzyme assays, with an IC50 of 113 μM. Enniatin B also reduces activation of ERK (p44/p42).

Aurofusarin is a secondary metabolite produced by Fusarium graminearum, a prominent fungal pathogen in temperate climate regions that affects major crops. In addition to aurofusarin, Fusarium graminearum synthesizes several other compounds, including monomethylsorbitol, zearalenone C, antibiotic Y, 2-amino-14,16-dimethyloctadecan-3-ol (2-AOD-3-ol), gibberellin, and enniatin.