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Results for "

endoplasmic reticulum (er) proteostasis

" in TargetMol Product Catalog.
  • Inhibitors & Agonists
    3
    TargetMol | All_Pathways
  • IXA4
    T93491185329-96-7
    IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1. IXA4-stimulated IRE1 activation also enhanced pancreatic function.
    • $34
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    TargetMol | Citations Cited
  • AA147
    ATF6-activator-147
    T14080393121-74-9
    AA147 (ATF6-activator-147) is a small molecule endoplasmic reticulum (ER) proteostasis regulator. The selectively activates ATF6 arm of the unfolded protein response (UPR) .It acts as a prodrug that preferentially triggers ATF6 signaling through a mechanism involving localized metabolic activation and selective covalent modification of ER resident proteins that regulate ATF6 activity.
    • $35
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    TargetMol | Citations Cited
  • ER proteostasis regulator-1
    T82450912777-95-8
    ER proteostasis regulator-1 is an effective modulator of ER proteostasis. It balances the UPR pathway to reduce misfolded protein accumulation, protecting cells from proteotoxicity in neurodegenerative disease research.
    • $40
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