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encorafenib

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Encorafenib
LGX818
T64871269440-17-6
Encorafenib (LGX818) is an orally available mutated BRaf V600E inhibitor(IC50=0.3 nM) with potential antineoplastic activity.
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Encorafenib-13C,d3
TMID-1113
Encorafenib-13C,d3 is a version of Encorafenib labeled with 13C and deuterium. Encorafenib (LGX818) is a potent BRAF inhibitor, exhibiting selective antiproliferative and pro-apoptotic activity against BRAFV600E cells, with an EC50 value of 4 nM.
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