en 106

EN106, a potent FEM1B inhibitor and a cysteine-reactive covalent ligand, effectively disrupts the recognition of FEM1B's crucial reductive stress substrate, FNIP1.

TX-1123 is a potent inhibitor of protein tyrosine kinase (PTK), specifically targeting Src, eEF2-K, PKA, and EGFR-K/PKC. Additionally, it acts as a cyclo-oxygenase (COX) inhibitor, displaying IC50 values of 1.16 μM for COX2 and 15.7 μM for COX1, indicating a higher affinity towards COX2. With low mitochondrial toxicity, TX-1123 is beneficial for cancer research applications.

MEN-10627 is a polycyclic peptide and tachykinin NK2 receptor antagonist.

MEN-10612 is a cyclic pseudopeptide and potent tachykinin NK-2 receptor antagonist.

WIN 66306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes. It binds to NK1 and NK2 receptors and inhibits contractions induced by substance P in isolated guinea pig ileum in a concentration-dependent manner.