einecs-200-707-6

Aspirin calcium is the prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Aspirin-D4 is the deuterated form of Aspirin. Aspirin (T0005) acts as a non-selective and irreversible inhibitor of COX-1 and COX-2, with IC50 values of 5 μg/mL and 210 μg/mL, respectively.

Aspirin-D4 (Standard) is a reference standard of Aspirin-D4 intended for quantitative analysis, quality control, and related biochemical research applications. Aspirin-d4 is the deuterated form of Aspirin. Aspirin acts as a non-selective and irreversible inhibitor of COX-1 and COX-2, with IC50 values of 5 μg/mL and 210 μg/mL, respectively.

Aspirin is an orally active, selective, and irreversible inhibitor of COX-1 and COX-2 with IC₅₀ values of 5 and 210 μg/mL, respectively. It induces apoptosis, inhibits NF-κB activation and platelet prostaglandin synthesis, thereby preventing thrombosis. Additionally, it acts as a histone deacetylase inhibitor that upregulates p21, exhibiting anti-inflammatory, antipyretic, analgesic, and anti-platelet aggregation activities. Aspirin is commonly used to induce gastric ulcer models.

Aspirin-D3 is a deuterated form of Aspirin. Aspirin (T0005) itself acts as a non-selective and irreversible inhibitor of COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively.

Aspirin-D3 (Standard) is a reference standard of Aspirin-D3 intended for quantitative analysis, quality control, and related biochemical research applications. Aspirin-d3 is a deuterated form of Aspirin. Aspirin itself acts as a non-selective and irreversible inhibitor of COX-1 and COX-2, with IC50 values of 5 and 210 μg/mL, respectively.