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By Target- Estrogen Receptor/ERR
- Estrogen/progestogen Receptor(2)
- Aromatase(1)
- Drug Metabolite(1)
- Parasite(1)
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Results for "
e-endoxifen
" in TargetMol Product Catalog- Inhibitors & Agonists3
Endoxifen (E-isomer)
Endoxifen E-isomer, E-Endoxifen
T11200114828-90-9
Endoxifen E-isomer (E-Endoxifen) is the E-isomer of (Z)-Endoxifen. Endoxifen E-isomer has antiestrogenic effects.
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Endoxifen E-isomer hydrochloride
E-Endoxifen hydrochloride
T36451197194-61-8
Endoxifen E-isomer hydrochloride (E-Endoxifen hydrochloride), a tamoxifen metabolite, is an effective and specific Estrogen Response Modifier (SERM).
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Endoxifen
(E Z)-N-desmethyl-4-hydroxy Tamoxifen, (E Z)-Endoxifen
T4281110025-28-0
(E Z)-Endoxifen ((E Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for estrogen receptors than tamoxifen. As the efficient conversion of tamoxifen to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.
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