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By Target- 5-HT Receptor
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Results for "
e-4424
" in TargetMol Product Catalog- Inhibitors & Agonists1
Lesopitron dihydrochloride
E4424
T11839132449-89-9
Lesopitron dihydrochloride with IC50 of 125 nM in rat hippocampal membranes, is a full and selective 5-HT1A receptor agonist.
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Lesopitron HCl(132449-89-9 Free base)
T11839L132449-88-8In house
Lesopitron HCl is a 5-HT1A receptor agonist with anxiolytic effects that reverses dark avoidance behavior associated with cocaine withdrawal in mice.
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T25672132449-46-8In house
Lesopitron is an anxiolytic with pre- and postsynaptic 5-HT1A agonist activity and is more effective than 5-HT1A agonists in rat social interaction and marmoset anxiety models. lesopitron counteracts benzodiazepine withdrawal-induced anxiety in rodents with low acute toxicity and does not potentiate the effects of alcohol or barbiturates.
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