dynorphin a acetate(80448 90 4 free base)

Dynorphin A is an endogenous opioid peptide and a κ-opioid receptor (KOR) agonist, with some agonistic activity on μ- and δ-opioid receptors. It primarily functions as a neurotransmitter and regulator in the central and peripheral nervous systems, exerting analgesic and mood-regulating effects.

Dynorphin A acetate is an Endogenous kappa receptor agonist.

Dynorphin A (1-10), an endogenous opioid neuropeptide, interacts with the κ-opioid receptor by binding to its extracellular loop 2 and inhibits NMDA-activated current, demonstrating an IC50 value of 42.0 μM.

Dynorphin A TFA, an endogenous opioid peptide, plays a role in inhibitory neurotransmission within the central nervous system (CNS). It acts as a highly potent kappa opioid receptor (KOR) agonist and also stimulates other opioid receptors, including mu (MOR) and delta (DOR). Furthermore, Dynorphin A TFA has been observed to induce neuronal death, making it a significant subject in neurological disease research [1] [2].

Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, binds in the transmembrane domain of the κ-receptor.

Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.