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dtp 348

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  • Inhibitors & Agonists
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crv431
T708111383420-08-3
CRV431 is a novel Pan-Cyclophilin Inhibitor, potently inhibiting all cyclophilin isoforms tested - A, B, D, and G (IC50 values ranged from 1-7 nM).
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10-14 weeks
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dtp348
T708131383370-92-0
DTP348 is an oral dual CAIX inhibitor radiosensitizer. DTP 348 is an oral dual drug with two mechanisms of action: (1). carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2). radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety.
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6-8 weeks
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