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dsp 6952

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
  • Isotope Products
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    TargetMol | Isotope_Products
DSP-6952
T713081184661-33-3
DSP-6952 is a 5-HT4 receptor partial agonist, inhibiting visceral hypersensitivity and ameliorating gastrointestinal dysfunction.
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10-14 weeks
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Gemfibrozil-d6
T713061184986-45-5
Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif ligand 2 (CCL2) in ApoE- - mice. Formulations containing gemfibrozil have been used in the treatment of high cholesterol.
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6-8 weeks
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