dotap

DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) is a useful and effective cationic lipid transfection DNA(plasmids, BacMIDs) and modified nucleic acids (antisense oligonucleotides) without the use of auxiliary lipids.

Fluorescent DOTAP, a cationic lipid, aids research in the delivery of nucleic acids and proteins [1].

DOTAP mesylate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

DOTAP methylsulfat is a cationic lipid reagent derived from trimethylammonium, featuring two 18-carbon fatty acid tails each with a single alkene group. This compound can self-assemble with negatively charged ions (such as DNA) to form complexes that adhere to cell membranes and enter cells through electrostatic interactions and endocytosis. With its hydrophobic domains, DOTAP methylsulfat facilitates the fusion of endosomal membranes to release DNA into the cytoplasm, serving a role in gene delivery. It is widely used in research areas like gene therapy, cell transfection, and the design of non-viral vectors.