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By Target- Histone Methyltransferase
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Results for "
dot1lin1
" in TargetMol Product Catalog- Inhibitors & Agonists1
Dot1L-IN-1
T110812088518-50-5
The Ki value of DOT1L-in-1 is 2pm.It is a highly effective, selective and novel Dot1L inhibitor.
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T73637
Dot1L-IN-1 TFA is a potent and selective Dot1L inhibitor, with a K i of 2 pM and an IC50 of <0.1 nM. It effectively inhibits H3K79 dimethylation (IC50 = 3 nM) and suppresses HoxA9 promoter activity (IC50 = 17 nM) in HeLa and Molm-13 cells, respectively [1].
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