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dm3sme

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  • Inhibitors & Agonists
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DM3-SMe
T11057796073-70-6
DM3-SMe, a maytansine derivative and tubulin inhibitor, acts as the cytotoxic component in antibody-drug conjugates (ADCs). It can bind to antibodies through disulfide bonds or stable thioether bonds and demonstrates high in vitro cytotoxic activity with an IC50 of 0.0011.
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