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By Target- Transferase
- Acyltransferase(1)
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Results for "
dgat 1 inhibitor 2
" in TargetMol Product Catalog- Inhibitors & Agonists2
DGAT-1 inhibitor 2 
T11016942999-61-3In house
DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor and anti-obesity drug. DGAT-1 (acyl-CoA: diacylglycerol acyltransferase 1) is one of two known DGAT enzymes that catalyze the final step of triglyceride synthesis. Transgenic mice and pharmacological studies indicate that inhibiting DGAT1 is a promising strategy for treating obesity and type 2 diabetes.
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A 922500
DGAT-1 Inhibitor 4a, A922500
T6365959122-11-3
A 922500 (DGAT-1 Inhibitor 4a) is an inhibitor of human and mouse DGAT-1 with IC50 values of 7 nM and 24 nM, respectively, demonstrating good selectivity over related acyltransferases, hERG, and a panel of anti-targets.
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