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deubiquitinating enzymes (dubs)

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
RA-9
T8464919091-63-7
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs) with a favorable toxicity profile and anticancer activity, particularly effective in inducing apoptosis in ovarian cancer cell lines.
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Ub4ix
TP28732396736-46-0
Ub4ix, a DUB 26S proteasome inhibitor, safeguards K48-linked Ub chains against cleavage by deubiquitinating enzymes (DUBs) and inhibits the proteasomal degradation of Ub-tagged proteins. Additionally, it diminishes the viability of Hela cells and triggers apoptosis, exhibiting an IC 50 value of 1.6 μM.
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