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- Inhibitors & Agonists1
DMDA-PatA
Desmethyl-desamino-pateamine A
T200734
DMDA-PatA is a small-molecule inhibitor of eIF4A, a DEAD-box RNA-binding protein. It functions by clamping eIF4A onto the GNG motif in an mRNA-selective and ATP-independent manner, thereby inhibiting translation. DMDA-PatA holds potential for applications in cancer and viral infection research.
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