derythrosphingosine

D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator

GlcCer (d18:1/18:0) (C18 Glucosyl(β) ceramide (d18:1/18:0)) is a sphingolipid with potential applications in research on Parkinson's disease and Lewy body dementia.

C8 Ceramide, a cell-permeable analog, is analog to naturally occur ceramides.

C12-Ceramide (C12 Ceramide (d18:1/12:0)), a ceramide present in the protective membranes surrounding umbilical cord blood vessels in infants born to women with pre-eclampsia, can be used to assess the level of ASM activity in the plasma of patients with Niemann-Pick disease.

D-erythro-Sphingosine hydrochloride, also known as Erythrosphingosine, serves as a specific TRPM3 activator and induces retinoblastoma protein dephosphorylation.

C18 Ceramide-1-phosphate (d18:1/18:0) is a long-chain molecule identified in murine skin, promoting the migration of mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells (HUVECs) at concentrations of 0.5 to 5 µM. It exhibits elevated levels in CFPAC-1 pancreatic ductal adenocarcinoma cells compared to pancreatic cancer stem cells, and its myocardial concentration is heightened in Langendorff isolated perfused mouse hearts under an ex vivo ischemia model.

Sphingosine (d18:1), an amino alcohol, is chiefly recognized for its 18-carbon unsaturated hydrocarbon chain. Nevertheless, in mammalian tissues, both sphingosine and its variant, dihydrosphingosine, feature hydrocarbon chains ranging from 12 to 26 carbons. Sphingosine (d15:1) represents a naturally rare variant, serving as an internal standard for chromatographic or spectrometric analyses of sphingoid compounds.

Sphingosine (d16:1), an unconventional sphingolipid, is synthesized through enzymatic reactions starting with the condensation of myristoyl-CoA and serine by serine palmitoyltransferase long-chain base subunit 3 (SPTLC3), which shows a preference for myristoyl-CoA. This compound is found in minute quantities in its free form in human plasma and as a component of various plasma sphingolipids, such as sphingosine-1-phosphate, ceramides, sphingomyelins, and in brain cerebrosides, albeit at lower concentrations than the more common d18:1 sphingoid base. Sphingosine (d16:1) acts as an inhibitor of PKC in mixed micelle assays and diminishes superoxide production triggered by phorbol 12-myristate 13-acetate in isolated human neutrophils, as well as inhibiting the growth of CHO cells with IC50 values of 1 and 3.2 µM, respectively. Additionally, the concentration of sphingolipids containing sphingosine (d16:1) in the plasma is linked to the dietary consumption of saturated fatty acids and protein among ethnic Chinese populations.

N,N-dihexyl Sphingosine (d18:1/6:0/6:0) is a lipid molecule that can be used in life science related research. The CAS number of N,N-dihexyl Sphingosine (d18:1/6:0/6:0) is 2377379-53-6.

C15 Ceramide (d18:1/15:0) is a lipid molecule that can be used in life science related research. The CAS number of C15 Ceramide (d18:1/15:0) is 67492-15-3.

C10 Ceramide (d18:1/10:0) is a lipid molecule that can be used in life science related research. The CAS number of C10 Ceramide (d18:1/10:0) is 111122-57-7.

C32 Ceramide (d18:1/32:0) is a lipid molecule that can be used in life science related research. The CAS number of C32 Ceramide (d18:1/32:0) is 34227-73-1.

C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) is a lipid molecule that can be used in life science related research. The CAS number of C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) is 890041-50-6.

C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) is a lipid molecule that can be used in life science related research. The CAS number of C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) is 34249-41-7.

C6 Biotin Ceramide (d18:1/6:0) is a lipid molecule used in life science-related research.

N-Boc-1-pivaloyl-D-erythro-sphingosine is a reagent used in biochemical reactions.

C6 Ceramide (d18:1/6:0) alkyne is an ω-alkyne derivative of C6 ceramide. The terminal alkyne group enables it to participate in click chemistry reactions, facilitating the labeling of C6 ceramide with fluorescent tags or biotin. This allows for analysis of C6 ceramide's metabolism and biological activity.

D-erythro-Sphingosine-13C2,D2 is a deuterium-labeled form of D-erythro-Sphingosine (T5891). This compound, also known as Erythrosphingosine, serves as a highly effective activator of p32 kinase, with an EC50 of 8 μM. It acts as an inhibitor of protein kinase C (PKC) and also functions as an activator of PP2A.

D-erythro-Sphingosine-D7 is the deuterated form of D-erythro-Sphingosine. D-erythro-Sphingosine (T5891) (Erythrosphingosine) is a potent activator of p32 kinase, with an EC50 of 8 μM, and acts as an inhibitor of protein kinase C (PKC).

C20 Ceramide (d18:1/20:0)/N-arachidoyl-D-erythro-sphingosine (Standard) is a reference standard of C20 Ceramide (d18:1/20:0)/N-arachidoyl-D-erythro-sphingosine intended for quantitative analysis, quality control, and related biochemical research applications.

C18:1 Ceramide-D7(D18:1-D7/18:1(9Z) N-Oleoyl-D-Erythro-Sphingosine-D7 (Standard) is a reference standard of C18:1 Ceramide-D7(D18:1-D7/18:1(9Z) N-Oleoyl-D-Erythro-Sphingosine-D7 intended for quantitative analysis, quality control, and related biochemical research applications.