deoxynivalenol

Deoxynivalenol (Vomitoxin) is an orally active mycotoxin belonging to the trichothecenes family, which traverses the intestinal mucosa via the paracellular pathway without being affected by P-gp/MRP, used for research on gastrointestinal inflammation such as diarrhea and vomiting.

15-Acetyl-deoxynivalenol, a highly toxic trichothecene found in cereals, exhibits toxicity to HepG2 cells.

Deoxynivalenol-3-β-D-glucoside (DON-3-β-D-glucoside) is a plant metabolite of the Fusarium mycotoxin Deoxynivalenol, exhibiting lower toxicity than Deoxynivalenol in vitro and in vivo [1][2].

Deepoxy-deoxynivalenol is Metabolite of deoxynivalenol. Deepoxydeoxynivalenol is a macrocyclic polyol compound for proteomics research. Environmental contaminants; Food contaminants.

3-Acetyldeoxynivalenol is a mycotoxin discovered in F. graminearum that can penetrate the blood-brain barrier and induce necrosis in mouse duodenal and spleen cells.

4-deoxy Nivalenol-13C15 is intended for use as an internal standard for the quantification of 4-deoxy nivalenol by GC- or LC-MS. 4-deoxy Nivalenol (T15097) is a trichothecene mycotoxin that has been found inFusarium.1It binds to eukaryotic ribosomes and inhibits protein synthesis in mice when administered at doses ranging from 5 to 25 mg/kg. 4-deoxy Nivalenol (T15097) (0.1 and 0.2 mg/kg) induces emesis in pigs and decreases feed consumption in pigs when administered at a dose of 40 ppb in the diet.2It induces lethality in mice (LD50= 46-78 mg/kg).34-deoxy Nivalenol has been found inF. graminearum-infected cereal grains such as wheat, barley, and corn.

3-Acetyldeoxy Nivalenol-13C17 is intended for use as an internal standard for the quantification of 3-Acetyldeoxy Nivalenol (T13493) by GC- or LC-MS. 3-Acetyldeoxy Nivalenol is a mycotoxin that has been found in F. graminearum.

WML-01 is a fungicide with EC50 values of 0.079 μg/mL, 0.72 μg/mL, and 2.02 μg/mL against F. graminearum, F. fujikuroi, and S. sclerotiorum, respectively. It disrupts the cell membrane of F. graminearum and induces lipid droplet deposition. WML-01 inhibits the biosynthesis of deoxynivalenol (DON) without cross-resistance and significantly impedes the assembly of ribosomal subunits, thereby hindering protein synthesis. WML-01 effectively controls the spread of Fusarium head blight (FHB) in wheat.

13C15-Nivalenol is intended for use as an internal standard for the quantification of nivalenol by GC- or LC-MS. Nivalenol (T13797) is a trichothecene mycotoxin that has been found inFusarium.1It is lethal to mice (LD50= 6.9 mg/kg).2Nivalenol (5, 10, and 15 mg/kg) also induces thymic, splenic, and Peyer's patch cell apoptosis in mice.3

Vomitoxin-BSA (DON-BSA) is a synthetic antigen composed of Deoxynivalenol (Vomitoxin) and bovine serum albumin (BSA). Deoxynivalenol is one of the most significant mycotoxins linked to the food chain. Vomitoxin-BSA serves as a tool in the production of monoclonal antibodies against Deoxynivalenol.