decursinol

Decursinol is isolated from the roots of Angelica Gigas with an antinociceptive effect. It also has anti-tumor and anti-metastasis activity.

(±)-Decursinol (3',4'-dihydro-3'-hydroxy-Xanthyletin) is a natural product from Angelica gigas.

(-)-Decursinol (Aegelinol; (-)-Smyrinol) is a natural pyranocoumarin compound that can be extracted from the roots of Apiaceae family plants, such as Ferulago campestris. It exhibits inhibitory effects against both Gram-positive bacteria (such as Staphylococcus aureus ATCC 13709 and Enterococcus faecalis ATCC 14428) and Gram-negative bacteria (such as Salmonella typhii ATCC 19430, Enterobacter cloacae ATCC 10699, and Enterobacter aerogenes ATCC 13048) with a minimum inhibitory concentration (MIC) range of 16 to 64 μg/mL. Additionally, (-)-Decursinol possesses antioxidant activity and can be utilized in bacterial infection research.

Decursinol (Standard) is a reference standard for research and analysis in studies involving Decursinol. Decursinol is isolated from the roots of Angelica Gigas with an antinociceptive effect. It also has anti-tumor and anti-metastasis activity.

Decursinol angelate (Standard) is a reference standard for research and analysis in studies involving Decursinol angelate. Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer cells through modulation of PI3K/AKT, ERK and NF-kappaB, its anti-inflammatory activity may contribute to its anti-cancer activity.

Decursinol angelate has anti-tumor, anti-inflammatory, anti-oxidant, and hepatoprotective activities, it inhibits VEGF-induced angiogenesis via suppression of the VEGFR-2-signaling pathway; it also suppresses invasion and inflammatory activation of cancer

1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 induced NOX activation and Smad signaling. 3. Decursin has anti-cancer activity , mediated suppression of the PKCα, MAPK and NF-κB pathways in MCF-7 cells. 4. Decursin exhibits cytotoxicity against various human cancer cells and to possess anti-amnesic activity in vivo through the inhibition of AChE activity.

Decursinol 3-Methyl-3-butenoic acid is a natural product that can be used in related research in the field of life sciences. Its product number is TN8813.