dbco peg4 mmaf

DBCO-PEG4-MMAF is an antibody-drug conjugate (ADC) component that exhibits potent antitumor activity. It combines the tubulin polymerization inhibitor MMAF with a cleavable linker, DBCO-PEG4, to target cancer cells effectively.

DBCO-PEG4-VC-PAB-MMAF is a click-reactive Drug-linker that contains a DBCO group and can undergo a strain-promoted acetylene-nitride cycloaddition reaction (SPAAC) with molecules containing an Azide group. MMAF is an effective inhibitor of microtubulin polymerization. DBCO-PEG4-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs).

DBCO-PEG4-Val-Cit-PAB-MMAF is a chemical compound consisting of a cleavable 4 unit polyethylene glycol antibody-drug conjugate (ADC) linker (DBCO-PEG4-Val-Cit-PAB) and a potent inhibitor of tubulin polymerization (MMAF). This compound is an essential component in the synthesis of ADCs.

DBCO-PEG4-VC-PAB-MMAD is a click-reactive Drug-linker that contains a DBCO group and can undergo a strain-promoted acetylene-nitride cycloaddition reaction (SPAAC) with molecules containing an Azide group. MMAD is an effective microtubule (tubulin) inhibitor. DBCO-PEG4-VC-PAB-MMAF, DBCO-PEG4-VC-PAB-MMAD can be used in the synthesis of antibody-drug conjugates (ADC).