dapl in 1

DapL-IN-1 is an inhibitor of L,L-diaminopimelate aminotransferase (DapL), suppressing bacterial and plant DapL activity. DapL-IN-1 shows species-dependent inhibitory sensitivity and provides a basis for developing new antibiotics, herbicides, or algicides, with low toxicity to animals. The differences in binding mode of DapL-IN-1 near active-site residues contribute to this varied biological activity.